Profound hypothermia with circulatory arrest

Profound hypothermia with prolonged circulatory arrest. An experimental study.

Aprotinin in aortic surgery requiring profound hypothermia and circulatory arrest.

OBJECTIVE The use of aprotinin in cardiac surgery to improve haemostasis and reduce blood loss particularly in patient groups at increased risk of bleeding is well established. Previous retrospective studies in profound hypothermic surgery have highlighted concerns that in this circumstances aprotinin may paradoxically cause increased bleeding and intravascular thrombosis. We therefore adopted ...

Intellectual performance in children after circulatory arrest with profound hypothermia in infancy.

38 children were assessed 22 months to 6 years after open heart surgery using circulatory arrest with deep hypothermia. The mean IQ of the group was 99.2 (SD 19.5). No correlation was found between IQ and the age or weight at operation or the duration of circulatory arrest. The results suggest that the technique gives effective protection to the brain during periods of circulatory arrest for up...

The sympathetic response to profound hypothermia and circulatory arrest in infants.

It has been suggested that the increased incidence of ventricular arrhythmias recognized below 30 degrees C might be catecholamine mediated. Elevate catecholamine concentrations have been reported in experimentally induced hypothermia in animals. Plasma concentrations of epinephrine and norepinephrine were measured during profound hypothermia and total circulatory arrest in infants under one ye...

Use of profound hypothermia and circulatory arrest for the calcified aorta.

This case report discusses one method of dealing with the extensively calcified aorta in patients undergoing open heart surgery. Profound hypothermia and circulatory arrest was used in a patient undergoing aortic valve replacement with severe calcification of the ascending aorta and transverse arch. This patient recovered from surgery and was discharged from the hospital with no neurologic defi...